Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links
C de Jorge Martínez, G Rukh, MJ Williams… - Journal of Genetics and …, 2022 - Elsevier
… the study was well-powered, suggesting that they may not be involved in aetiology of AN. …
This study identified 77 genome-wide significant loci for body fat percentage (BF%) and 174 …
This study identified 77 genome-wide significant loci for body fat percentage (BF%) and 174 …
Suggestive evidence for causal effect of leptin levels on Risk for anorexia nervosa: results of a mendelian randomization study
… of the most recent genome-wide association study (GWAS) for … Our study was stimulated by
recent case reports suggesting … not implicate a causal effect. AN itself has no causal effect on …
recent case reports suggesting … not implicate a causal effect. AN itself has no causal effect on …
Genetics and neurobiology of eating disorders
… the most recent genome-wide association study (GWAS) of … VTA region 112 , implicating that
a loss of leptin signaling in VTA … suggest an overlap in the biological regulation of AN, leptin, …
a loss of leptin signaling in VTA … suggest an overlap in the biological regulation of AN, leptin, …
[PDF][PDF] GENETICS IN ANOREXIA NERVOSA.
IM Sabau, NI Andreescu, A Chiriță-Emandi… - Jurnalul …, 2021 - jurnalulpediatrului.ro
… Therefore, this study suggested that a dysregulation in leptin signaling may … genome-wide
association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin …
association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin …
Examining the shared etiology of psychopathology with genome-wide association studies
TT Mallard, AD Grotzinger… - Physiological …, 2023 - journals.physiology.org
… -wide pattern of downward dysregulation in autism spectrum disorder (120… loci in the brain
(51) (ie, variants involved in the regulation of a gene’s expression), and it has been suggested …
(51) (ie, variants involved in the regulation of a gene’s expression), and it has been suggested …
Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment
… studies along with genome-wide association studies have identified several genetic loci
involved … and motor hyperactivity are both major features of AN, suggesting a possible …
involved … and motor hyperactivity are both major features of AN, suggesting a possible …
[HTML][HTML] Reframing anorexia nervosa as a metabo-psychiatric disorder
CM Bulik, IM Carroll, P Mehler - Trends in Endocrinology & Metabolism, 2021 - cell.com
… Studies of intestinal morphology also suggest disturbances in gut … Genome-wide association
study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa…
study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa…
Genetics of Eating Disorders
… A genome-wide association study of anorexia nervosa suggests a risk locus implicated in
dysregulated leptin signaling. Scientific Reports, 7(1), 3847. https://doi.org/ 10.1038/s41598-…
dysregulated leptin signaling. Scientific Reports, 7(1), 3847. https://doi.org/ 10.1038/s41598-…
The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
D van der Meer, TP Gurholt, IE Sønderby… - Communications …, 2022 - nature.com
… loci with distributed effects across the body composition measures and 241 significant genes
primarily involved … Our findings suggest a strong genetic component to these associations, …
primarily involved … Our findings suggest a strong genetic component to these associations, …
[HTML][HTML] The utility of animal models for studying the metabo-psychiatric origins of anorexia nervosa
… A recent large-scale genome-wide association study (GWAS… as well as psychiatric origins,
suggesting that AN should be … implicated in the regulation of activity-based anorexia. Solid …
suggesting that AN should be … implicated in the regulation of activity-based anorexia. Solid …